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Shoot the Messenger! A New Phage Weapon to Neutralize the Type III CRISPR Immune Response.
Shilton, Amanda K; Marraffini, Luciano A.
Affiliation
  • Shilton AK; Laboratory of Bacteriology, The Rockefeller University, 1230 York Ave, New York, NY, USA.
  • Marraffini LA; Laboratory of Bacteriology, The Rockefeller University, 1230 York Ave, New York, NY, USA; Howard Hughes Medical Institute, The Rockefeller University, 1230 York Ave, New York, NY, USA. Electronic address: marraffini@rockefeller.edu.
Mol Cell ; 78(4): 568-569, 2020 05 21.
Article in En | MEDLINE | ID: mdl-32442502
Athukoralage et al. (2020) identify a new anti-CRISPR (Acr) that degrades cA4, a cyclic oligo-adenylate second messenger produced during the type III CRISPR immune response. This provides an effective way by which invaders can bypass downstream CRISPR effectors that rely on this signaling molecule.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteriophages / Clustered Regularly Interspaced Short Palindromic Repeats Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteriophages / Clustered Regularly Interspaced Short Palindromic Repeats Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos