Your browser doesn't support javascript.
loading
The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2.
Tutuncuoglu, Beril; Cakir, Merve; Batra, Jyoti; Bouhaddou, Mehdi; Eckhardt, Manon; Gordon, David E; Krogan, Nevan J.
Affiliation
  • Tutuncuoglu B; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California.
  • Cakir M; The J. David Gladstone Institutes, San Francisco, California.
  • Batra J; Quantitative Biosciences Institute, University of California, San Francisco, California.
  • Bouhaddou M; QBI COVID-19 Research Group (QCRG), San Francisco, California.
  • Eckhardt M; The Cancer Cell Map Initiative (CCMI), University of California, San Francisco, California, and University of California, San Diego, La Jolla, California.
  • Gordon DE; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California.
  • Krogan NJ; The J. David Gladstone Institutes, San Francisco, California.
Cancer Discov ; 10(7): 916-921, 2020 07.
Article in En | MEDLINE | ID: mdl-32444466
ABSTRACT
The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Drug Repositioning / Betacoronavirus / Neoplasm Proteins / Neoplasms Limits: Humans Language: En Journal: Cancer Discov Year: 2020 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Drug Repositioning / Betacoronavirus / Neoplasm Proteins / Neoplasms Limits: Humans Language: En Journal: Cancer Discov Year: 2020 Document type: Article