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PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice.
Holt, Marie K; Cook, Daniel R; Brierley, Daniel I; Richards, James E; Reimann, Frank; Gourine, Alexander V; Marina, Nephtali; Trapp, Stefan.
Affiliation
  • Holt MK; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK.
  • Cook DR; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK.
  • Brierley DI; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK.
  • Richards JE; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK.
  • Reimann F; Wellcome Trust/MRC Institute of Metabolic Science (IMS), Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Gourine AV; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK.
  • Marina N; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK. Electronic address: n.marina@ucl.ac.uk.
  • Trapp S; Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, UCL, London, UK. Electronic address: s.trapp@ucl.ac.uk.
Mol Metab ; 39: 101024, 2020 09.
Article in En | MEDLINE | ID: mdl-32446875
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tachycardia / Solitary Nucleus / Proglucagon / Glucagon-Like Peptide-1 Receptor / Heart Rate / Neurons Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2020 Document type: Article Affiliation country: Reino Unido Country of publication: Alemania
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tachycardia / Solitary Nucleus / Proglucagon / Glucagon-Like Peptide-1 Receptor / Heart Rate / Neurons Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2020 Document type: Article Affiliation country: Reino Unido Country of publication: Alemania