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Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism.
Zhou, Qingxin; Lin, Meihua; Feng, Xing; Ma, Fei; Zhu, Yuekun; Liu, Xing; Qu, Chao; Sui, Hong; Sun, Bei; Zhu, Anlong; Zhang, Heng; Huang, He; Gao, Zhi; Zhao, Yongxiang; Sun, Jiangyun; Bai, Yuxian; Jin, Junfei; Hong, Xuehui; Zou, Chang; Zhang, Zhiyong.
Affiliation
  • Zhou Q; The Affiliated Hospital of Guilin Medical University, Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Guangxi Neurological Diseases Clinical Research Center, Guilin, Guangxi, China.
  • Lin M; Department of Gastrointestinal Oncology, Harbin Medical University Cancer Hospital, Harbin, China.
  • Feng X; Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ.
  • Ma F; Research Center of Clinical Pharmacy, State Key Laboratory for Diagnosis and Treatment of Infectious Disease, First Affiliated Hospital, Zhejiang University, Hangzhou, China.
  • Zhu Y; Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, First Affiliated Hospital, Zhejiang University, Hangzhou, China.
  • Liu X; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
  • Qu C; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Sui H; Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Sun B; Key Laboratory of Hepatosplenic Surgery, Harbin Medical University, Ministry of Education, Harbin, China.
  • Zhu A; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Zhang H; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun, China.
  • Huang H; Department of Gastrointestinal Oncology, Harbin Medical University Cancer Hospital, Harbin, China.
  • Gao Z; Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Zhao Y; Key Laboratory of Hepatosplenic Surgery, Harbin Medical University, Ministry of Education, Harbin, China.
  • Sun J; Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Bai Y; Department of Histology and Embryology, Xiang Ya School of Medicine, Central South University, Changsha, Hunan, China.
  • Jin J; Department of Histology and Embryology, Xiang Ya School of Medicine, Central South University, Changsha, Hunan, China.
  • Hong X; National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Guangxi Medical University, Nanning, China.
  • Zou C; National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Guangxi Medical University, Nanning, China.
  • Zhang Z; Department of Acupuncture, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
J Exp Med ; 217(8)2020 08 03.
Article in En | MEDLINE | ID: mdl-32453420
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Tacrine / Bile Duct Neoplasms / Protein-Tyrosine Kinases / Drug Delivery Systems / Protein Serine-Threonine Kinases / Cholangiocarcinoma / Cellular Reprogramming Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Exp Med Year: 2020 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Tacrine / Bile Duct Neoplasms / Protein-Tyrosine Kinases / Drug Delivery Systems / Protein Serine-Threonine Kinases / Cholangiocarcinoma / Cellular Reprogramming Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Exp Med Year: 2020 Document type: Article Affiliation country: China