Your browser doesn't support javascript.
loading
Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening.
Ammar, Usama M; Abdel-Maksoud, Mohammed S; Ali, Eslam M H; Mersal, Karim I; Ho Yoo, Kyung; Oh, Chang-Hyun.
Affiliation
  • Ammar UM; Center for Biomaterials, Korea Institute of Science & Technology (KIST School), Seoul, Seongbuk-gu 02792, Republic of Korea; University of Science & Technology (UST), Daejeon, Yuseong-gu 34113, Republic of Korea; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian Univer
  • Abdel-Maksoud MS; Medicinal & Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (NRC), Dokki, Giza 12622, Egypt.
  • Ali EMH; Center for Biomaterials, Korea Institute of Science & Technology (KIST School), Seoul, Seongbuk-gu 02792, Republic of Korea; University of Science & Technology (UST), Daejeon, Yuseong-gu 34113, Republic of Korea.
  • Mersal KI; Center for Biomaterials, Korea Institute of Science & Technology (KIST School), Seoul, Seongbuk-gu 02792, Republic of Korea; University of Science & Technology (UST), Daejeon, Yuseong-gu 34113, Republic of Korea.
  • Ho Yoo K; Chemical Kinomics Research Center, Korea Institute of Science and Technology, Seoul, Republic of Korea.
  • Oh CH; Center for Biomaterials, Korea Institute of Science & Technology (KIST School), Seoul, Seongbuk-gu 02792, Republic of Korea; University of Science & Technology (UST), Daejeon, Yuseong-gu 34113, Republic of Korea. Electronic address: choh@kist.re.kr.
Bioorg Chem ; 100: 103967, 2020 07.
Article in En | MEDLINE | ID: mdl-32470760
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Proto-Oncogene Proteins B-raf / Protein Kinase Inhibitors / Imidazoles Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Proto-Oncogene Proteins B-raf / Protein Kinase Inhibitors / Imidazoles Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Country of publication: Estados Unidos