[Mesothelial proliferation of the tunica vaginalis testis]. / Mesotheliale Proliferate der Tunica vaginalis testis.
Pathologe
; 41(4): 406-410, 2020 Jul.
Article
in De
| MEDLINE
| ID: mdl-32472158
ABSTRACT
Proliferative changes seen in reactive mesothelial hyperplasia of a hydrocele sac may mimic malignant mesothelioma. There is no immunohistochemical staining that reliably separates benign from malignant mesothelial proliferations. However, the combined analysis of BAP1 by immunohistochemistry and CDKN2A by FISH has been reported to yield both a high specificity and sensitivity in this differential diagnosis. In addition, the evaluation of risk factors such as asbestos exposure or prior traumata may be helpful for the correct diagnosis. Exclusion of stromal invasion, which is diagnostic for malign mesothelioma, is of utmost importance. Therefore, extended histological workup is essential.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Testicular Neoplasms
/
Lung Neoplasms
/
Mesothelioma
Type of study:
Diagnostic_studies
/
Risk_factors_studies
Limits:
Humans
/
Male
Language:
De
Journal:
Pathologe
Year:
2020
Document type:
Article