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Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs.
Kang, Dongwei; Sun, Yanying; Murugan, N Arul; Feng, Da; Wei, Fenju; Li, Jing; Jiang, Xiangyi; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng; Liu, Xinyong.
Affiliation
  • Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
  • Sun Y; Suzhou Research Institute, Shandong University, Room 522, Building H of NUSP, No. 388 Ruoshui Road, SIP, 215123 Suzhou, Jiangsu, P.R. China.
  • Murugan NA; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
  • Feng D; Department of Theoretical Chemistry and Biology, School of Chemistry, Biotechnology and Health,, KTH Royal Institute of Technology, S-106 91 Stockholm, Sweden.
  • Wei F; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
  • Li J; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
  • Jiang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
  • De Clercq E; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
  • Pannecouque C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium.
  • Zhan P; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium.
  • Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
ACS Infect Dis ; 6(8): 2225-2234, 2020 08 14.
Article in En | MEDLINE | ID: mdl-32619096
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV-1 / Anti-HIV Agents Limits: Humans Language: En Journal: ACS Infect Dis Year: 2020 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV-1 / Anti-HIV Agents Limits: Humans Language: En Journal: ACS Infect Dis Year: 2020 Document type: Article Country of publication: Estados Unidos