PARC report: a perspective on the state of clinical pharmacogenomics testing.
Pharmacogenomics
; 21(11): 809-820, 2020 07.
Article
in En
| MEDLINE
| ID: mdl-32635876
ABSTRACT
In this Perspective, the authors discuss the state of pharmacogenomics testing addressing a number of advances, challenges and barriers, including legal ramifications, changes to the regulatory landscape, coverage of testing and the implications of direct-to-consumer genetic testing on the provision of care to patients. Patient attitudes toward pharmacogenomics testing and associated costs will play an increasingly important role in test acquisition and subsequent utilization in a clinical setting. Additional key steps needed include further research trials demonstrating clinical utility and cost-effectiveness of pharmacogenetic testing, evidence review to better integrate genomic information into clinical practice guidelines in target therapeutic areas to help providers identify patients that may benefit from pharmacogenetic testing and engagement with payers to create a path to reimbursement for pharmacogenetic tests that currently have sufficient evidence of clinical utility. Increased adoption of testing by payers and improved reimbursement practices will be needed to overcome barriers, especially as the healthcare landscape continues to shift toward a system of value-based care.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Precision Medicine
/
Direct-To-Consumer Screening and Testing
/
Pharmacogenomic Testing
Type of study:
Guideline
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Pharmacogenomics
Journal subject:
FARMACOLOGIA
/
GENETICA MEDICA
Year:
2020
Document type:
Article
Affiliation country:
Estados Unidos