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TRPV4 Inhibition and CRISPR-Cas9 Knockout Reduce Inflammation Induced by Hyperphysiological Stretching in Human Annulus Fibrosus Cells.
Cambria, Elena; Arlt, Matthias J E; Wandel, Sandra; Krupkova, Olga; Hitzl, Wolfgang; Passini, Fabian S; Hausmann, Oliver N; Snedeker, Jess G; Ferguson, Stephen J; Wuertz-Kozak, Karin.
Affiliation
  • Cambria E; Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland.
  • Arlt MJE; Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland.
  • Wandel S; Department of Orthopedics, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.
  • Krupkova O; Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland.
  • Hitzl W; Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland.
  • Passini FS; Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.
  • Hausmann ON; Spine Surgery, University Hospital Basel, 4031 Basel, Switzerland.
  • Snedeker JG; Research Office (Biostatistics), Paracelsus Medical University, 5020 Salzburg, Austria.
  • Ferguson SJ; Department of Ophthalmology and Optometry, Paracelsus Medical University, 5020 Salzburg, Austria.
  • Wuertz-Kozak K; Research Program Experimental Ophthalmology and Glaucoma Research, Paracelsus Medical University, 5020 Salzburg, Austria.
Cells ; 9(7)2020 07 21.
Article in En | MEDLINE | ID: mdl-32708074
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Mechanical / TRPV Cation Channels / Gene Knockout Techniques / CRISPR-Cas Systems / Annulus Fibrosus / CRISPR-Associated Protein 9 Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cells Year: 2020 Document type: Article Affiliation country: Suiza
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Mechanical / TRPV Cation Channels / Gene Knockout Techniques / CRISPR-Cas Systems / Annulus Fibrosus / CRISPR-Associated Protein 9 Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cells Year: 2020 Document type: Article Affiliation country: Suiza