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Eeyarestatin 24 impairs SecYEG-dependent protein trafficking and inhibits growth of clinically relevant pathogens.
Steenhuis, Maurice; Koningstein, Gregory M; Oswald, Julia; Pick, Tillman; O'Keefe, Sarah; Koch, Hans-Georg; Cavalié, Adolfo; Whitehead, Roger C; Swanton, Eileithyia; High, Stephen; Luirink, Joen.
Affiliation
  • Steenhuis M; Department of Molecular Microbiology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit, Amsterdam, the Netherlands.
  • Koningstein GM; Department of Molecular Microbiology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit, Amsterdam, the Netherlands.
  • Oswald J; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Pick T; Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany.
  • O'Keefe S; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • Koch HG; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Cavalié A; Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany.
  • Whitehead RC; School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, UK.
  • Swanton E; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • High S; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • Luirink J; Department of Molecular Microbiology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit, Amsterdam, the Netherlands.
Mol Microbiol ; 115(1): 28-40, 2021 01.
Article in En | MEDLINE | ID: mdl-32798330
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SEC Translocation Channels / Hydrazones / Hydroxyurea Language: En Journal: Mol Microbiol Journal subject: BIOLOGIA MOLECULAR / MICROBIOLOGIA Year: 2021 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SEC Translocation Channels / Hydrazones / Hydroxyurea Language: En Journal: Mol Microbiol Journal subject: BIOLOGIA MOLECULAR / MICROBIOLOGIA Year: 2021 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido