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Baricitinib restrains the immune dysregulation in patients with severe COVID-19.
Bronte, Vincenzo; Ugel, Stefano; Tinazzi, Elisa; Vella, Antonio; De Sanctis, Francesco; Canè, Stefania; Batani, Veronica; Trovato, Rosalinda; Fiore, Alessandra; Petrova, Varvara; Hofer, Francesca; Barouni, Roza Maria; Musiu, Chiara; Caligola, Simone; Pinton, Laura; Torroni, Lorena; Polati, Enrico; Donadello, Katia; Friso, Simonetta; Pizzolo, Francesca; Iezzi, Manuela; Facciotti, Federica; Pelicci, Pier Giuseppe; Righetti, Daniela; Bazzoni, Paolo; Rampudda, Mariaelisa; Comel, Andrea; Mosaner, Walter; Lunardi, Claudio; Olivieri, Oliviero.
Affiliation
  • Bronte V; Immunology Section, Department of Medicine.
  • Ugel S; Immunology Section, Department of Medicine.
  • Tinazzi E; Internal Medicine Section B, Department of Medicine.
  • Vella A; Immunology Section, Department of Medicine.
  • De Sanctis F; Immunology Section, Department of Medicine.
  • Canè S; Immunology Section, Department of Medicine.
  • Batani V; Immunology Section, Department of Medicine.
  • Trovato R; Immunology Section, Department of Medicine.
  • Fiore A; Immunology Section, Department of Medicine.
  • Petrova V; Immunology Section, Department of Medicine.
  • Hofer F; Immunology Section, Department of Medicine.
  • Barouni RM; Immunology Section, Department of Medicine.
  • Musiu C; Immunology Section, Department of Medicine.
  • Caligola S; Immunology Section, Department of Medicine.
  • Pinton L; Immunology Section, Department of Medicine.
  • Torroni L; Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.
  • Polati E; Intensive Care Unit, Department of Surgery, Dentistry, Maternity and Infant, University and Hospital Trust of Verona, Verona, Italy.
  • Donadello K; Intensive Care Unit, Department of Surgery, Dentistry, Maternity and Infant, University and Hospital Trust of Verona, Verona, Italy.
  • Friso S; Internal Medicine Section B, Department of Medicine.
  • Pizzolo F; Internal Medicine Section B, Department of Medicine.
  • Iezzi M; Center for Advanced Studies and Technology (CAST), University of G. D'Annunzio of Chieti-Pescara, Chieti, Italy.
  • Facciotti F; Department of Experimental Oncology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.
  • Pelicci PG; Department of Experimental Oncology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.
  • Righetti D; Pederzoli Hospital, Peschiera sul Garda, Italy.
  • Bazzoni P; Pederzoli Hospital, Peschiera sul Garda, Italy.
  • Rampudda M; Pederzoli Hospital, Peschiera sul Garda, Italy.
  • Comel A; Pederzoli Hospital, Peschiera sul Garda, Italy.
  • Mosaner W; Pederzoli Hospital, Peschiera sul Garda, Italy.
  • Lunardi C; Internal Medicine Section B, Department of Medicine.
  • Olivieri O; Internal Medicine Section B, Department of Medicine.
J Clin Invest ; 130(12): 6409-6416, 2020 12 01.
Article in En | MEDLINE | ID: mdl-32809969
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Pyrazoles / Sulfonamides / Azetidines / Off-Label Use / SARS-CoV-2 / COVID-19 / COVID-19 Drug Treatment Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Aspects: Ethics Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2020 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Pyrazoles / Sulfonamides / Azetidines / Off-Label Use / SARS-CoV-2 / COVID-19 / COVID-19 Drug Treatment Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Aspects: Ethics Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2020 Document type: Article