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Bavachinin inhibits cholesterol synthesis enzyme FDFT1 expression via AKT/mTOR/SREBP-2 pathway.
Dong, Xi; Zhu, Yue; Wang, Shan; Luo, Yun; Lu, Shan; Nan, Fengwei; Sun, Guibo; Sun, Xiaobo.
Affiliation
  • Dong X; Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China; Key Laboratory of New Drug Discovery B
  • Zhu Y; Harbin University of Commerce, Harbin, PR China.
  • Wang S; Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China; Key Laboratory of New Drug Discovery B
  • Luo Y; Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China; Key Laboratory of New Drug Discovery B
  • Lu S; Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China; Key Laboratory of New Drug Discovery B
  • Nan F; Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China.
  • Sun G; Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China; Key Laboratory of New Drug Discovery B
  • Sun X; Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China; Key Laboratory of New Drug Discovery B
Int Immunopharmacol ; 88: 106865, 2020 Nov.
Article in En | MEDLINE | ID: mdl-32827918
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Farnesyl-Diphosphate Farnesyltransferase / Flavonoids / Cholesterol / Proto-Oncogene Proteins c-akt / Sterol Regulatory Element Binding Protein 2 / TOR Serine-Threonine Kinases / Anticholesteremic Agents Limits: Humans Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2020 Document type: Article Country of publication: Países Bajos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Farnesyl-Diphosphate Farnesyltransferase / Flavonoids / Cholesterol / Proto-Oncogene Proteins c-akt / Sterol Regulatory Element Binding Protein 2 / TOR Serine-Threonine Kinases / Anticholesteremic Agents Limits: Humans Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2020 Document type: Article Country of publication: Países Bajos