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Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma.
Ng, Harry Ho Man; Lee, Ren Yuan; Goh, Siting; Tay, Isabel Shu Ying; Lim, Xinru; Lee, Bernett; Chew, Valerie; Li, Huihua; Tan, Benedict; Lim, Sherlly; Lim, Jeffrey Chun Tatt; Au, Bijin; Loh, Josh Jie Hua; Saraf, Sahil; Connolly, John Edward; Loh, Tracy; Leow, Wei Qiang; Lee, Joycelyn Jie Xin; Toh, Han Chong; Malavasi, Fabio; Lee, Ser Yee; Chow, Pierce; Newell, Evan W; Choo, Su Pin; Tai, David; Yeong, Joe; Lim, Tony Kiat Hon.
Affiliation
  • Ng HHM; Duke-NUS Medical School, Singapore.
  • Lee RY; Division of Pathology, Singapore General Hospital, Singapore.
  • Goh S; Division of Pathology, Singapore General Hospital, Singapore.
  • Tay ISY; Nanyang Technological University, Singapore.
  • Lim X; Division of Pathology, Singapore General Hospital, Singapore.
  • Lee B; Temasek Polytechnic, Singapore.
  • Chew V; Institute of Molecular Cell Biology (IMCB), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Li H; Singapore Immunology Network (SIgN), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Tan B; Duke-NUS Medical School, Singapore.
  • Lim S; SingHealth Translational Immunology and Inflammation Centre (STIIC), Singapore Health Services Pte Ltd, Singapore.
  • Lim JCT; Division of Medicine, Singapore General Hospital, Singapore.
  • Au B; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
  • Loh JJH; Institute of Molecular Cell Biology (IMCB), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Saraf S; Institute of Molecular Cell Biology (IMCB), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Connolly JE; Institute of Molecular Cell Biology (IMCB), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Loh T; Institute of Molecular Cell Biology (IMCB), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Leow WQ; Division of Pathology, Singapore General Hospital, Singapore.
  • Lee JJX; Division of Pathology, Singapore General Hospital, Singapore.
  • Toh HC; Institute of Molecular Cell Biology (IMCB), Agency of Science, Technology and Research (A*STAR), Singapore.
  • Malavasi F; Division of Pathology, Singapore General Hospital, Singapore.
  • Lee SY; Division of Pathology, Singapore General Hospital, Singapore.
  • Chow P; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
  • Newell EW; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
  • Choo SP; Laboratory of Immunogenetics and CeRMS, Department of Medical Sciences, University of Torino, Torino, Italy.
  • Tai D; Duke-NUS Medical School, Singapore.
  • Yeong J; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore.
  • Lim TKH; Duke-NUS Medical School, Singapore.
J Immunother Cancer ; 8(2)2020 08.
Article in En | MEDLINE | ID: mdl-32847986

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunohistochemistry / Carcinoma, Hepatocellular / ADP-ribosyl Cyclase 1 / Tumor Microenvironment / B7-H1 Antigen / Immunotherapy / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: J Immunother Cancer Year: 2020 Document type: Article Affiliation country: Singapur Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunohistochemistry / Carcinoma, Hepatocellular / ADP-ribosyl Cyclase 1 / Tumor Microenvironment / B7-H1 Antigen / Immunotherapy / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: J Immunother Cancer Year: 2020 Document type: Article Affiliation country: Singapur Country of publication: Reino Unido