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Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine.
Micoli, Francesca; Bjarnarson, Stefania P; Arcuri, Melissa; Aradottir Pind, Audur Anna; Magnusdottir, Gudbjorg J; Necchi, Francesca; Di Benedetto, Roberta; Carducci, Martina; Schiavo, Fabiola; Giannelli, Carlo; Pisoni, Ivan; Martin, Laura B; Del Giudice, Giuseppe; MacLennan, Calman A; Rappuoli, Rino; Jonsdottir, Ingileif; Saul, Allan.
Affiliation
  • Micoli F; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Bjarnarson SP; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.
  • Arcuri M; Department of Immunology, Landspitali, The National University Hospital of Iceland, 101 Reykjavik, Iceland.
  • Aradottir Pind AA; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Magnusdottir GJ; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.
  • Necchi F; Department of Immunology, Landspitali, The National University Hospital of Iceland, 101 Reykjavik, Iceland.
  • Di Benedetto R; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.
  • Carducci M; Department of Immunology, Landspitali, The National University Hospital of Iceland, 101 Reykjavik, Iceland.
  • Schiavo F; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Giannelli C; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Pisoni I; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Martin LB; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Del Giudice G; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • MacLennan CA; R&D Centre, GSK Vaccines, 53100 Siena, Italy.
  • Rappuoli R; Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
  • Jonsdottir I; R&D Centre, GSK Vaccines, 53100 Siena, Italy.
  • Saul A; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom.
Proc Natl Acad Sci U S A ; 117(39): 24443-24449, 2020 09 29.
Article in En | MEDLINE | ID: mdl-32900928
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Salmonella typhi / Bacterial Proteins / Typhoid Fever / T-Lymphocytes / Salmonella Vaccines Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Salmonella typhi / Bacterial Proteins / Typhoid Fever / T-Lymphocytes / Salmonella Vaccines Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos