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Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity.
Kouam, Arnaud Fondjo; Owona, Brice Ayissi; Fifen, Rodrigue; Njayou, Frédéric Nico; Moundipa, Paul Fewou.
Affiliation
  • Kouam AF; Medical Research and Applied Biochemistry Laboratory, Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea, PO Box 63, Buea, Cameroon.
  • Owona BA; Laboratory of Molecular Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon.
  • Fifen R; Laboratory of Molecular Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon.
  • Njayou FN; Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon.
  • Moundipa PF; Laboratory of Molecular Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon.
Heliyon ; 6(8): e04602, 2020 Aug.
Article in En | MEDLINE | ID: mdl-32904230
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Heliyon Year: 2020 Document type: Article Affiliation country: Camerún Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Heliyon Year: 2020 Document type: Article Affiliation country: Camerún Country of publication: Reino Unido