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A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade.
Chen, Ivy X; Newcomer, Kathleen; Pauken, Kristen E; Juneja, Vikram R; Naxerova, Kamila; Wu, Michelle W; Pinter, Matthias; Sen, Debattama R; Singer, Meromit; Sharpe, Arlene H; Jain, Rakesh K.
Affiliation
  • Chen IX; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Newcomer K; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Pauken KE; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Juneja VR; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115.
  • Naxerova K; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Wu MW; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115.
  • Pinter M; Center for Systems Biology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Sen DR; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Singer M; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Jain RK; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 117(38): 23684-23694, 2020 09 22.
Article in En | MEDLINE | ID: mdl-32907939
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Tumor Microenvironment / Immunotherapy / Mammary Neoplasms, Experimental Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Tumor Microenvironment / Immunotherapy / Mammary Neoplasms, Experimental Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Document type: Article Country of publication: Estados Unidos