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Cell type-specific genetic regulation of gene expression across human tissues.
Kim-Hellmuth, Sarah; Aguet, François; Oliva, Meritxell; Muñoz-Aguirre, Manuel; Kasela, Silva; Wucher, Valentin; Castel, Stephane E; Hamel, Andrew R; Viñuela, Ana; Roberts, Amy L; Mangul, Serghei; Wen, Xiaoquan; Wang, Gao; Barbeira, Alvaro N; Garrido-Martín, Diego; Nadel, Brian B; Zou, Yuxin; Bonazzola, Rodrigo; Quan, Jie; Brown, Andrew; Martinez-Perez, Angel; Soria, José Manuel; Getz, Gad; Dermitzakis, Emmanouil T; Small, Kerrin S; Stephens, Matthew; Xi, Hualin S; Im, Hae Kyung; Guigó, Roderic; Segrè, Ayellet V; Stranger, Barbara E; Ardlie, Kristin G; Lappalainen, Tuuli.
Affiliation
  • Kim-Hellmuth S; Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany. skimhellmuth@gmail.com tlappalainen@nygenome.org.
  • Aguet F; New York Genome Center, New York, NY, USA.
  • Oliva M; Department of Systems Biology, Columbia University, New York, NY, USA.
  • Muñoz-Aguirre M; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Kasela S; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Wucher V; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.
  • Castel SE; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain.
  • Hamel AR; Department of Statistics and Operations Research, Universitat Politècnica de Catalunya (UPC), Barcelona, Catalonia, Spain.
  • Viñuela A; New York Genome Center, New York, NY, USA.
  • Roberts AL; Department of Systems Biology, Columbia University, New York, NY, USA.
  • Mangul S; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain.
  • Wen X; New York Genome Center, New York, NY, USA.
  • Wang G; Department of Systems Biology, Columbia University, New York, NY, USA.
  • Barbeira AN; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Garrido-Martín D; Ocular Genomics Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
  • Nadel BB; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Zou Y; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Bonazzola R; Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.
  • Quan J; Swiss Institute of Bioinformatics, Geneva, Switzerland.
  • Brown A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Martinez-Perez A; Department of Computer Science, University of California, Los Angeles, Los Angeles, CA, USA.
  • Soria JM; Department of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, Los Angeles, CA, USA.
  • Getz G; Department of Human Genetics, University of Chicago, Chicago, IL, USA.
  • Dermitzakis ET; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Small KS; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain.
  • Stephens M; Department of Molecular, Cellular, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Xi HS; Department of Statistics, University of Chicago, Chicago, IL, USA.
  • Im HK; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Guigó R; Inflammation & Immunology, Pfizer, Cambridge, MA, USA.
  • Segrè AV; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Stranger BE; Population Health and Genomics, University of Dundee, Dundee, Scotland, UK.
  • Ardlie KG; Unit of Genomic of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
  • Lappalainen T; Unit of Genomic of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
Science ; 369(6509)2020 09 11.
Article in En | MEDLINE | ID: mdl-32913075
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Quantitative Trait Loci / Transcriptome Type of study: Prognostic_studies Limits: Humans Language: En Journal: Science Year: 2020 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Quantitative Trait Loci / Transcriptome Type of study: Prognostic_studies Limits: Humans Language: En Journal: Science Year: 2020 Document type: Article Country of publication: Estados Unidos