Your browser doesn't support javascript.
loading
Optically Controlled Living Micromotors for the Manipulation and Disruption of Biological Targets.
Xin, Hongbao; Zhao, Nan; Wang, Yunuo; Zhao, Xiaoting; Pan, Ting; Shi, Yang; Li, Baojun.
Affiliation
  • Xin H; Institute of Nanophotonics, Jinan University, Guangzhou 511443, China.
  • Zhao N; Institute of Nanophotonics, Jinan University, Guangzhou 511443, China.
  • Wang Y; Department of Nephrology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
  • Zhao X; Institute of Nanophotonics, Jinan University, Guangzhou 511443, China.
  • Pan T; Institute of Nanophotonics, Jinan University, Guangzhou 511443, China.
  • Shi Y; Institute of Nanophotonics, Jinan University, Guangzhou 511443, China.
  • Li B; Institute of Nanophotonics, Jinan University, Guangzhou 511443, China.
Nano Lett ; 20(10): 7177-7185, 2020 10 14.
Article in En | MEDLINE | ID: mdl-32935992
Bioinspired and biohybrid micromotors represent a revolution in microrobotic research and are playing an increasingly important role in biomedical applications. In particular, biological micromotors that are multifunctional and can perform complex tasks are in great demand. Here, we report living and multifunctional micromotors based on single cells (green microalgae: Chlamydomonas reinhardtii) that are controlled by optical force. The micromotor's locomotion can be carefully controlled in a variety of biological media including cell culture medium, saliva, human serum, plasma, blood, and bone marrow fluid. It exhibits the capabilities to perform multiple tasks, in particular, indirect manipulation of biological targets and disruption of biological aggregates including in vitro blood clots. These micromotors can also act as elements in reconfigurable motor arrays where they efficiently work collaboratively and synchronously. This work provides new possibilities for many in vitro biomedical applications including target manipulation, cargo delivery and release, and biological aggregate removal.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Nano Lett Year: 2020 Document type: Article Affiliation country: China Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Nano Lett Year: 2020 Document type: Article Affiliation country: China Country of publication: Estados Unidos