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Decrease in matrix metalloproteinase­3 activity in systemic sclerosis fibroblasts causes α2­antiplasmin and extracellular matrix deposition, and contributes to fibrosis development.
Niwa, Hirofumi; Kanno, Yosuke; Shu, En; Seishima, Mariko.
Affiliation
  • Niwa H; Department of Dermatology, Gifu University Graduate School of Medicine, Gifu 501­1194, Japan.
  • Kanno Y; Department of Dermatology, Gifu University Graduate School of Medicine, Gifu 501­1194, Japan.
  • Shu E; Department of Dermatology, Gifu University Graduate School of Medicine, Gifu 501­1194, Japan.
  • Seishima M; Department of Dermatology, Gifu University Graduate School of Medicine, Gifu 501­1194, Japan.
Mol Med Rep ; 22(4): 3001-3007, 2020 Oct.
Article in En | MEDLINE | ID: mdl-32945390
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scleroderma, Systemic / Alpha-2-Antiplasmin / Matrix Metalloproteinase 3 / Extracellular Matrix Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Mol Med Rep Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Grecia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scleroderma, Systemic / Alpha-2-Antiplasmin / Matrix Metalloproteinase 3 / Extracellular Matrix Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Mol Med Rep Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Grecia