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A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver.
Wang, Lawrence T; Pereira, Lais S; Flores-Garcia, Yevel; O'Connor, James; Flynn, Barbara J; Schön, Arne; Hurlburt, Nicholas K; Dillon, Marlon; Yang, Annie S P; Fabra-García, Amanda; Idris, Azza H; Mayer, Bryan T; Gerber, Monica W; Gottardo, Raphael; Mason, Rosemarie D; Cavett, Nicole; Ballard, Reid B; Kisalu, Neville K; Molina-Cruz, Alvaro; Nelson, Jorgen; Vistein, Rachel; Barillas-Mury, Carolina; Amino, Rogerio; Baker, David; King, Neil P; Sauerwein, Robert W; Pancera, Marie; Cockburn, Ian A; Zavala, Fidel; Francica, Joseph R; Seder, Robert A.
Affiliation
  • Wang LT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Pereira LS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Flores-Garcia Y; Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  • O'Connor J; Department of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 0200, Australia; The Australian National University Medical School, Canberra, ACT 2601, Australia.
  • Flynn BJ; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Schön A; Department of Biology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Hurlburt NK; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Dillon M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Yang ASP; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Fabra-García A; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Idris AH; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Mayer BT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Gerber MW; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Gottardo R; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Mason RD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Cavett N; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Ballard RB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kisalu NK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Molina-Cruz A; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
  • Nelson J; Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Vistein R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Barillas-Mury C; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
  • Amino R; Unit of Malaria Infection and Immunity, Institut Pasteur, 25-28 Rue du Dr Roux, 75015 Paris, France.
  • Baker D; Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • King NP; Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Sauerwein RW; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Pancera M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Cockburn IA; Department of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 0200, Australia.
  • Zavala F; Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  • Francica JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Seder RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: rseder@mail.nih.gov.
Immunity ; 53(4): 733-744.e8, 2020 10 13.
Article in En | MEDLINE | ID: mdl-32946741
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Antibodies, Protozoan / Protozoan Proteins / Sporozoites / Antibodies, Neutralizing / Antibodies, Monoclonal / Antimalarials Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Antibodies, Protozoan / Protozoan Proteins / Sporozoites / Antibodies, Neutralizing / Antibodies, Monoclonal / Antimalarials Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos