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A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity.
Ding, Xiaoyu; Gu, Wanjian; Zhong, Yujie; Hao, Xiaoyao; Liu, Jinyu; Xia, Shukai; Luo, Lan; Chen, Mingjiu; Zhang, Chunni.
Affiliation
  • Ding X; Department of Clinical Laboratory, Jinling Hospital, State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangs
  • Gu W; Department of Clinical Laboratory, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
  • Zhong Y; Department of Clinical Laboratory, Jinling Hospital, State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangs
  • Hao X; Biosion Inc., Nanjing, Jiangsu, China.
  • Liu J; Biosion Inc., Nanjing, Jiangsu, China.
  • Xia S; Biosion Inc., Nanjing, Jiangsu, China.
  • Luo L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China. Electronic address: lanluo@nju.edu.cn.
  • Chen M; Biosion Inc., Nanjing, Jiangsu, China. Electronic address: mingjiu.chen@biosion.com.
  • Zhang C; Department of Clinical Laboratory, Jinling Hospital, State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangs
EBioMedicine ; 60: 102996, 2020 Oct.
Article in En | MEDLINE | ID: mdl-32950002
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Screening Assays, Antitumor / Receptor, ErbB-2 / Antineoplastic Agents, Immunological Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans Language: En Journal: EBioMedicine Year: 2020 Document type: Article Country of publication: Países Bajos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Screening Assays, Antitumor / Receptor, ErbB-2 / Antineoplastic Agents, Immunological Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans Language: En Journal: EBioMedicine Year: 2020 Document type: Article Country of publication: Países Bajos