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KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.
Wong, Jasmine C; Perez-Mancera, Pedro A; Huang, Tannie Q; Kim, Jangkyung; Grego-Bessa, Joaquim; Del Pilar Alzamora, Maria; Kogan, Scott C; Sharir, Amnon; Keefe, Susan H; Morales, Carolina E; Schanze, Denny; Castel, Pau; Hirose, Kentaro; Huang, Guo N; Zenker, Martin; Sheppard, Dean; Klein, Ophir D; Tuveson, David A; Braun, Benjamin S; Shannon, Kevin.
Affiliation
  • Wong JC; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
  • Perez-Mancera PA; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.
  • Huang TQ; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
  • Kim J; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
  • Grego-Bessa J; Intercellular Signaling in Cardiovascular Development and Disease Laboratory, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
  • Del Pilar Alzamora M; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
  • Kogan SC; Department of Laboratory Medicine and.
  • Sharir A; Program in Craniofacial Biology and Department of Orofacial Sciences, University of California, San Francisco, California, USA.
  • Keefe SH; Program in Craniofacial Biology and Department of Orofacial Sciences, University of California, San Francisco, California, USA.
  • Morales CE; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
  • Schanze D; Institute of Human Genetics, University Hospital Magdeburg, Magdeburg, Germany.
  • Castel P; Helen Diller Family Comprehensive Cancer Center.
  • Hirose K; Cardiovascular Research Institute.
  • Huang GN; Department of Physiology, and.
  • Zenker M; Cardiovascular Research Institute.
  • Sheppard D; Department of Physiology, and.
  • Klein OD; Institute of Human Genetics, University Hospital Magdeburg, Magdeburg, Germany.
  • Tuveson DA; Cardiovascular Research Institute.
  • Braun BS; Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Shannon K; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
JCI Insight ; 5(21)2020 11 05.
Article in En | MEDLINE | ID: mdl-32990679
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Craniosynostoses / Hematologic Diseases / Lung Diseases / Mutation / Cardiomyopathies Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: JCI Insight Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Craniosynostoses / Hematologic Diseases / Lung Diseases / Mutation / Cardiomyopathies Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: JCI Insight Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos