Environment Influences Tumor Progression and Transcriptional Subtype in a New Model of Pancreatic Cancer.
Cancer Discov
; 10(10): 1448-1450, 2020 10.
Article
in En
| MEDLINE
| ID: mdl-33004478
ABSTRACT
In this issue, Miyabayashi and colleagues describe a novel intraductal model of pancreatic cancer that allows modeling of the transcriptional subtypes of pancreatic cancer. Using this model, they are able to observe subtype switching driven by the microenvironment, a process at least partially mediated by RAS signaling.See related article by Miyabayashi et al., p. 1566.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatic Neoplasms
/
Carcinoma, Pancreatic Ductal
Limits:
Humans
Language:
En
Journal:
Cancer Discov
Year:
2020
Document type:
Article
Affiliation country:
Reino Unido