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APCCDC20-mediated degradation of PHD3 stabilizes HIF-1a and promotes tumorigenesis in hepatocellular carcinoma.
Shi, Min; Dai, Wei-Qi; Jia, Rong-Rong; Zhang, Qing-Hui; Wei, Jue; Wang, Yu-Gang; Xiang, Shi-Hao; Liu, Bin; Xu, Ling.
Affiliation
  • Shi M; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China.
  • Dai WQ; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China.
  • Jia RR; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China.
  • Zhang QH; Department of Clinical Laboratory, Kunshan First People's Hospital, Jiangsu University, Kunshan, 215300, China.
  • Wei J; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China.
  • Wang YG; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China.
  • Xiang SH; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China.
  • Liu B; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China. Electronic address: liubin@jou.edu.cn.
  • Xu L; Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200336, China. Electronic address: xuling82@shsmu.edu.cn.
Cancer Lett ; 496: 144-155, 2021 01 01.
Article in En | MEDLINE | ID: mdl-33039559
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / Carcinoma, Hepatocellular / Hypoxia-Inducible Factor 1, alpha Subunit / Cdc20 Proteins / Hypoxia-Inducible Factor-Proline Dioxygenases / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Lett Year: 2021 Document type: Article Affiliation country: China Country of publication: Irlanda
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / Carcinoma, Hepatocellular / Hypoxia-Inducible Factor 1, alpha Subunit / Cdc20 Proteins / Hypoxia-Inducible Factor-Proline Dioxygenases / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Lett Year: 2021 Document type: Article Affiliation country: China Country of publication: Irlanda