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Colocalization of tracks from boron neutron capture reactions and images of isolated cells.
Postuma, Ian; Sommi, Patrizia; Vitali, Agostina; Shu, Diyun; Martino, Greta di; Cansolino, Laura; Ferrari, Cinzia; Ricci, Vittorio; Magni, Chiara; Protti, Nicoletta; Fatemi, Setareh; Tamburini, Umberto Anselmi; Bortolussi, Silva; Altieri, Saverio.
Affiliation
  • Postuma I; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy. Electronic address: ian.postuma@pv.infn.it.
  • Sommi P; Department of Molecular Medicine, Human Physiology Unit, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Vitali A; Department of Chemistry, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Shu D; Department of Nuclear Science and Technology, Nanjing University of Aeronautics and Astronautics, Yudao Street 29, Nanjing, 210016, China.
  • Martino GD; Department of Chemistry, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Cansolino L; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy; Department of Clinic-Surgical Sciences, Experimental Surgery Laboratory, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.
  • Ferrari C; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy; Department of Clinic-Surgical Sciences, Experimental Surgery Laboratory, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.
  • Ricci V; Department of Molecular Medicine, Human Physiology Unit, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Magni C; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy; Department of Physics, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Protti N; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy.
  • Fatemi S; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy.
  • Tamburini UA; Department of Chemistry, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Bortolussi S; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy; Department of Physics, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
  • Altieri S; Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy; Department of Physics, University of Pavia, Corso Strada Nuova 65, Pavia, 27100, Italy.
Appl Radiat Isot ; 167: 109353, 2021 Jan.
Article in En | MEDLINE | ID: mdl-33039761
In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells. A neutron autoradiography technique is used, which combines images of cells with images of tracks produced in a solid-state nuclear track detector.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiometry / Boron Neutron Capture Therapy Limits: Humans Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2021 Document type: Article Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiometry / Boron Neutron Capture Therapy Limits: Humans Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2021 Document type: Article Country of publication: Reino Unido