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Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.
Guthmiller, Jenna J; Lan, Linda Yu-Ling; Fernández-Quintero, Monica L; Han, Julianna; Utset, Henry A; Bitar, Dalia J; Hamel, Natalie J; Stovicek, Olivia; Li, Lei; Tepora, Micah; Henry, Carole; Neu, Karlynn E; Dugan, Haley L; Borowska, Marta T; Chen, Yao-Qing; Liu, Sean T H; Stamper, Christopher T; Zheng, Nai-Ying; Huang, Min; Palm, Anna-Karin E; García-Sastre, Adolfo; Nachbagauer, Raffael; Palese, Peter; Coughlan, Lynda; Krammer, Florian; Ward, Andrew B; Liedl, Klaus R; Wilson, Patrick C.
Affiliation
  • Guthmiller JJ; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Lan LY; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
  • Fernández-Quintero ML; Center for Molecular Biosciences Innsbruck, Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, 6020 Innsbruck, Austria.
  • Han J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Utset HA; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Bitar DJ; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Hamel NJ; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Stovicek O; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Li L; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Tepora M; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Henry C; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Neu KE; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
  • Dugan HL; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
  • Borowska MT; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
  • Chen YQ; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Liu STH; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Stamper CT; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
  • Zheng NY; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Huang M; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • Palm AE; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
  • García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount S
  • Nachbagauer R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Palese P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Coughlan L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Microbiology and Immunology and Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Liedl KR; Center for Molecular Biosciences Innsbruck, Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, 6020 Innsbruck, Austria.
  • Wilson PC; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA. Electronic address: wilsonp@uchicago.edu.
Immunity ; 53(6): 1230-1244.e5, 2020 12 15.
Article in En | MEDLINE | ID: mdl-33096040
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Orthomyxoviridae / B-Lymphocytes / Broadly Neutralizing Antibodies Limits: Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Orthomyxoviridae / B-Lymphocytes / Broadly Neutralizing Antibodies Limits: Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos