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CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity.
Preece, Roland; Pavesi, Andrea; Gkazi, Soragia Athina; Stegmann, Kerstin A; Georgiadis, Christos; Tan, Zhi Ming; Aw, Jia Ying Joey; Maini, Mala K; Bertoletti, Antonio; Qasim, Waseem.
Affiliation
  • Preece R; Molecular and Cellular Immunology Unit, UCL Great Ormond Street Institute of Child Health, NIHR Great Ormond Street Hospital Biomedical Research Centre, 30 Guilford Street, London WC1N 1EH, UK.
  • Pavesi A; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR) 61 Biopolis Drive, Singapore 138673, Singapore.
  • Gkazi SA; Molecular and Cellular Immunology Unit, UCL Great Ormond Street Institute of Child Health, NIHR Great Ormond Street Hospital Biomedical Research Centre, 30 Guilford Street, London WC1N 1EH, UK.
  • Stegmann KA; UCL Division of Infection and Immunity, The Rayne Building, 5 University Street, London WC1E 6EJ, UK.
  • Georgiadis C; Molecular and Cellular Immunology Unit, UCL Great Ormond Street Institute of Child Health, NIHR Great Ormond Street Hospital Biomedical Research Centre, 30 Guilford Street, London WC1N 1EH, UK.
  • Tan ZM; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR) 61 Biopolis Drive, Singapore 138673, Singapore.
  • Aw JYJ; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR) 61 Biopolis Drive, Singapore 138673, Singapore.
  • Maini MK; UCL Division of Infection and Immunity, The Rayne Building, 5 University Street, London WC1E 6EJ, UK.
  • Bertoletti A; Program Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.
  • Qasim W; Singapore Immunology Network (SigN), Agency of Science Technology and Research (A∗STAR), Singapore, Singapore.
Mol Ther Methods Clin Dev ; 19: 149-161, 2020 Dec 11.
Article in En | MEDLINE | ID: mdl-33102612

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Mol Ther Methods Clin Dev Year: 2020 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Mol Ther Methods Clin Dev Year: 2020 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos