Gender influence on the MVV / FEVi ratio in a population of healthy young adults.
Physiol Rep
; 8(20): e14623, 2020 10.
Article
in En
| MEDLINE
| ID: mdl-33112050
ABSTRACT
INTRODUCTION:
Maximal voluntary ventilation (MVV) and flow expiratory volume in the first second (FEVi) are important spirometric parameters. They are both gender-dependent. However, estimating the MVV, which is widely practiced in cardiopulmonary function testing, by multiplying FEVi by a constant value (equal to MVV/FEVi ratio) does not seem to take this into account. The purpose of this study was to compare the MVV/FEVi ratio by gender among healthy young adults.METHODS:
This cross-sectional prospective study involved 67 medical sciences students, including 36 females of the same race, height, and age group. Their ventilatory function was assessed using a computerized spirometer, according to international recommendations. Pearson's test made it possible to correlate different spirometric parameters and linear regression was established between MVV and FEVi. The nonparametric Kruskal-Wallis test was used to compare the MVV/FEVi ratio between females and males. Comparisons by gender were made also between our data and previous prediction equations.RESULTS:
In both females and males, FEVi was the spirometric parameter with which MVV had the highest correlation (r = .91 in females, r = .63 in males). A comparison of the means of the MVV/FEVi ratio by gender showed a statistically significant (p < .005) decrease in females (35.68 vs. 38.87). The previous prediction equations showed statistically significant under and overestimation of MVV values when gender was not taken into account.CONCLUSION:
For the same height, age, and race, the ratio MVV/FEVi was significantly lower for females. So, the use of a preset constant value in estimating the MVV without taking gender into account was methodologically questionable. This work, which could have clinical implications, would benefit from being confirmed in a larger population.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Respiration
/
Spirometry
Type of study:
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspects:
Determinantes_sociais_saude
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Physiol Rep
Year:
2020
Document type:
Article