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Improved In Vitro-In Vivo Correlation by Using the Unbound-Fraction-Adjusted IC50 for Breast Cancer Resistance Protein Inhibition.
Imai, Shunji; Arai, Toshiki; Yamada, Tetsuhiro; Niwa, Makoto.
Affiliation
  • Imai S; Pharmacokinetics and Safety Assessment Department, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan. sy.imai@po.nippon-shinyaku.co.jp.
  • Arai T; Pharmacokinetics and Safety Assessment Department, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan.
  • Yamada T; Pharmacokinetics and Safety Assessment Department, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan.
  • Niwa M; Pharmacokinetics and Safety Assessment Department, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan.
Pharm Res ; 37(12): 230, 2020 Oct 29.
Article in En | MEDLINE | ID: mdl-33123823
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / Xenobiotics / ATP Binding Cassette Transporter, Subfamily G, Member 2 Limits: Animals Language: En Journal: Pharm Res Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / Xenobiotics / ATP Binding Cassette Transporter, Subfamily G, Member 2 Limits: Animals Language: En Journal: Pharm Res Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos