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Disruption of microRNA-214 during general anaesthesia prevents brain injury and maintains mitochondrial fusion by promoting Mfn2 interaction with Pkm2.
Liu, Tiejun; Wang, Bin; Li, Gai; Dong, Xiaoliu; Yu, Guannan; Qian, Qingzeng; Duan, Likun; Li, Hongxia; Jia, Zhao; Bai, Jing.
Affiliation
  • Liu T; Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Wang B; Department of Pediatrics, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Li G; CT Department, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Dong X; Department of Neurology, Tangshan People's Hospital, Tangshan, China.
  • Yu G; Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Qian Q; Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Duan L; Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Li H; Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
  • Jia Z; Department of Neurology, Tangshan People's Hospital, Tangshan, China.
  • Bai J; Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
J Cell Mol Med ; 24(23): 13589-13599, 2020 12.
Article in En | MEDLINE | ID: mdl-33147380
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvate Kinase / Brain Injuries / Mitochondrial Proteins / MicroRNAs / Mitochondrial Dynamics / GTP Phosphohydrolases / Anesthesia, General Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: China Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvate Kinase / Brain Injuries / Mitochondrial Proteins / MicroRNAs / Mitochondrial Dynamics / GTP Phosphohydrolases / Anesthesia, General Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: China Country of publication: Reino Unido