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DNA methylation of FTO promotes renal inflammation by enhancing m6A of PPAR-α in alcohol-induced kidney injury.
Yu, Ju-Tao; Hu, Xiao-Wei; Chen, Hai-Yong; Yang, Qin; Li, Hai-Di; Dong, Yu-Hang; Zhang, Yao; Wang, Jia-Nan; Jin, Juan; Wu, Yong-Gui; Li, Jun; Ge, Jin-Fang; Meng, Xiao-Ming.
Affiliation
  • Yu JT; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Hu XW; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Chen HY; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China.
  • Yang Q; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Li HD; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Dong YH; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Zhang Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Wang JN; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Jin J; School of Basic Medicine, Anhui Medical University, Hefei, 230032, China.
  • Wu YG; Department of Nephrology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
  • Li J; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China.
  • Ge JF; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China. Electronic address: gejinfang@ahmu.edu.
  • Meng XM; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, The Key Laboratory of Anti-Inflammatory of Immune Medicines, Ministry of Education, Hefei, 230032, China. Electronic address: mengxiaoming@ahmu.e
Pharmacol Res ; 163: 105286, 2021 01.
Article in En | MEDLINE | ID: mdl-33157234
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Ethanol / Alpha-Ketoglutarate-Dependent Dioxygenase FTO / Kidney Diseases Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2021 Document type: Article Affiliation country: China Country of publication: Países Bajos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Ethanol / Alpha-Ketoglutarate-Dependent Dioxygenase FTO / Kidney Diseases Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2021 Document type: Article Affiliation country: China Country of publication: Países Bajos