Your browser doesn't support javascript.
loading
Chronic administration of P2X7 receptor antagonist JNJ-47965567 delays disease onset and progression, and improves motor performance in ALS SOD1G93A female mice.
Ruiz-Ruiz, Cristina; García-Magro, Nuria; Negredo, Pilar; Avendaño, Carlos; Bhattacharya, Anindya; Ceusters, Marc; García, Antonio G.
Affiliation
  • Ruiz-Ruiz C; Instituto Teófilo Hernando, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain.
  • García-Magro N; Departamento de Farmacología, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain.
  • Negredo P; Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain.
  • Avendaño C; Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain.
  • Bhattacharya A; Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain.
  • Ceusters M; Neuroscience Therapeutic Area, Janssen Research and Development LLC., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • García AG; Neuroscience Therapeutic Area, Janssen Research and Development, a Division of Janssen Pharmaceutica NV, Beerse B-2340, Belgium.
Dis Model Mech ; 13(10)2020 10 30.
Article in En | MEDLINE | ID: mdl-33174532
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Niacinamide / Disease Progression / Receptors, Purinergic P2X7 / Purinergic P2X Receptor Antagonists / Amyotrophic Lateral Sclerosis / Motor Activity Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2020 Document type: Article Affiliation country: España Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Niacinamide / Disease Progression / Receptors, Purinergic P2X7 / Purinergic P2X Receptor Antagonists / Amyotrophic Lateral Sclerosis / Motor Activity Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2020 Document type: Article Affiliation country: España Country of publication: Reino Unido