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Systemic hypoxia inhibits T cell response by limiting mitobiogenesis via matrix substrate-level phosphorylation arrest.
Saragovi, Amijai; Abramovich, Ifat; Omar, Ibrahim; Arbib, Eliran; Toker, Ori; Gottlieb, Eyal; Berger, Michael.
Affiliation
  • Saragovi A; The Lautenberg center for Immunology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University Medical School, Jerusalem, Israel.
  • Abramovich I; The Ruth and Bruce Rappaport, Faculty of Medicine, Technion - Israel Institute of Technology, Jerusalem, Israel.
  • Omar I; The Lautenberg center for Immunology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University Medical School, Jerusalem, Israel.
  • Arbib E; The Lautenberg center for Immunology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University Medical School, Jerusalem, Israel.
  • Toker O; Faculty of Medicine, Hebrew University of Jerusalem; The Allergy and Immunology Unit, Shaare Zedek Medical Center, Jerusalem, Israel.
  • Gottlieb E; The Ruth and Bruce Rappaport, Faculty of Medicine, Technion - Israel Institute of Technology, Jerusalem, Israel.
  • Berger M; The Lautenberg center for Immunology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University Medical School, Jerusalem, Israel.
Elife ; 92020 11 23.
Article in En | MEDLINE | ID: mdl-33226340
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Phosphorylation / Organelle Biogenesis / Lymphocyte Activation / Adenosine Triphosphate / CD8-Positive T-Lymphocytes / Mitochondrial Proteins / Hypoxia / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Elife Year: 2020 Document type: Article Affiliation country: Israel
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Phosphorylation / Organelle Biogenesis / Lymphocyte Activation / Adenosine Triphosphate / CD8-Positive T-Lymphocytes / Mitochondrial Proteins / Hypoxia / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Elife Year: 2020 Document type: Article Affiliation country: Israel