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Identification of a Potent and Selective 5-HT1A Receptor Agonist with In Vitro and In Vivo Antinociceptive Activity.
Linciano, Pasquale; Sorbi, Claudia; Comitato, Antonella; Lesniak, Anna; Bujalska-Zadrozny, Magdalena; Pawlowska, Agata; Bielenica, Anna; Orzelska-Górka, Jolanta; Kedzierska, Ewa; Biala, Grazyna; Ronsisvalle, Simone; Limoncella, Silvia; Casarini, Livio; Cichero, Elena; Fossa, Paola; Satala, Grzegorz; Bojarski, Andrzej J; Brasili, Livio; Bardoni, Rita; Franchini, Silvia.
Affiliation
  • Linciano P; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.
  • Sorbi C; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.
  • Comitato A; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy.
  • Lesniak A; Department of Pharmacodynamics, Faculty of Pharmacy, Centre for Preclinical Research and Technology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
  • Bujalska-Zadrozny M; Department of Pharmacodynamics, Faculty of Pharmacy, Centre for Preclinical Research and Technology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
  • Pawlowska A; Department of Pharmacodynamics, Faculty of Pharmacy, Centre for Preclinical Research and Technology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
  • Bielenica A; Department of Biochemistry, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
  • Orzelska-Górka J; Department of Pharmacology and Pharmacodynamics, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, Chodzki 4A, 20-093 Lublin, Poland.
  • Kedzierska E; Department of Pharmacology and Pharmacodynamics, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, Chodzki 4A, 20-093 Lublin, Poland.
  • Biala G; Department of Pharmacology and Pharmacodynamics, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, Chodzki 4A, 20-093 Lublin, Poland.
  • Ronsisvalle S; Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, I-95125 Catania, Italy.
  • Limoncella S; Unit of Endocrinology, Department Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, via G. Campi 287, 41125 Modena, Italy.
  • Casarini L; Unit of Endocrinology, Department Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, via G. Campi 287, 41125 Modena, Italy.
  • Cichero E; Center for Genomic Research, University of Modena and Reggio Emilia, via G. Campi 287, 41125 Modena, Italy.
  • Fossa P; Department of Pharmacy, Medicinal Chemistry Section, School of Medical and Pharmaceutical Sciences, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
  • Satala G; Department of Pharmacy, Medicinal Chemistry Section, School of Medical and Pharmaceutical Sciences, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
  • Bojarski AJ; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12, Smetna Street, 31-343, Kraków, Poland.
  • Brasili L; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12, Smetna Street, 31-343, Kraków, Poland.
  • Bardoni R; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.
  • Franchini S; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy.
ACS Chem Neurosci ; 11(24): 4111-4127, 2020 12 16.
Article in En | MEDLINE | ID: mdl-33263393
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Receptor, Serotonin, 5-HT1A Type of study: Diagnostic_studies Limits: Animals Language: En Journal: ACS Chem Neurosci Year: 2020 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Receptor, Serotonin, 5-HT1A Type of study: Diagnostic_studies Limits: Animals Language: En Journal: ACS Chem Neurosci Year: 2020 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos