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Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma.
Dell'Anno, Irene; Martin, Sarah A; Barbarino, Marcella; Melani, Alessandra; Silvestri, Roberto; Bottaro, Maria; Paolicchi, Elisa; Corrado, Alda; Cipollini, Monica; Melaiu, Ombretta; Giordano, Antonio; Luzzi, Luca; Gemignani, Federica; Landi, Stefano.
Affiliation
  • Dell'Anno I; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Martin SA; Centre for Cancer Cell and Molecular Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
  • Barbarino M; Department of Medical Biotechnologies, University of Siena, 53100, Siena, Italy.
  • Melani A; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, 19122, USA.
  • Silvestri R; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Bottaro M; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Paolicchi E; Department of Medical Biotechnologies, University of Siena, 53100, Siena, Italy.
  • Corrado A; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Cipollini M; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Melaiu O; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Giordano A; Department of Biology, Genetic Unit, University of Pisa, 56126, Pisa, Italy.
  • Luzzi L; Immuno-Oncology Laboratory, Department of Paediatric Haematology/Oncology and of Cell and Gene Therapy, Ospedale Pediatrico Bambino Gesù, IRCCS, 00165, Rome, Italy.
  • Gemignani F; Department of Medical Biotechnologies, University of Siena, 53100, Siena, Italy.
  • Landi S; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, 19122, USA.
Invest New Drugs ; 39(3): 644-657, 2021 06.
Article in En | MEDLINE | ID: mdl-33300108
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pleural Neoplasms / Vidarabine / STAT1 Transcription Factor / Risedronic Acid / Mesothelioma / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Invest New Drugs Year: 2021 Document type: Article Affiliation country: Italia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pleural Neoplasms / Vidarabine / STAT1 Transcription Factor / Risedronic Acid / Mesothelioma / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Invest New Drugs Year: 2021 Document type: Article Affiliation country: Italia