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Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease.
Ozen, Ahmet; Kasap, Nurhan; Vujkovic-Cvijin, Ivan; Apps, Richard; Cheung, Foo; Karakoc-Aydiner, Elif; Akkelle, Bilge; Sari, Sinan; Tutar, Engin; Ozcay, Figen; Uygun, Dilara Kocacik; Islek, Ali; Akgun, Gamze; Selcuk, Merve; Sezer, Oya Balci; Zhang, Yu; Kutluk, Gunsel; Topal, Erdem; Sayar, Ersin; Celikel, Cigdem; Houwen, Roderick H J; Bingol, Aysen; Ogulur, Ismail; Eltan, Sevgi Bilgic; Snow, Andrew L; Lake, Camille; Fantoni, Giovanna; Alba, Camille; Sellers, Brian; Chauvin, Samuel D; Dalgard, Clifton L; Harari, Olivier; Ni, Yan G; Wang, Ming-Dauh; Devalaraja-Narashimha, Kishor; Subramanian, Poorani; Ergelen, Rabia; Artan, Reha; Guner, Sukru Nail; Dalgic, Buket; Tsang, John; Belkaid, Yasmine; Ertem, Deniz; Baris, Safa; Lenardo, Michael J.
Affiliation
  • Ozen A; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey. ahmet.ozen@marmara.edu.tr.
  • Kasap N; Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Turkey. ahmet.ozen@marmara.edu.tr.
  • Vujkovic-Cvijin I; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey. ahmet.ozen@marmara.edu.tr.
  • Apps R; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey.
  • Cheung F; Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Turkey.
  • Karakoc-Aydiner E; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.
  • Akkelle B; Metaorganism Immunity Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Sari S; Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation, NIH, Bethesda, MD, USA.
  • Tutar E; Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation, NIH, Bethesda, MD, USA.
  • Ozcay F; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey.
  • Uygun DK; Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Turkey.
  • Islek A; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.
  • Akgun G; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey.
  • Selcuk M; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, School of Medicine, Gazi University, Ankara, Turkey.
  • Sezer OB; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey.
  • Zhang Y; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Baskent University Hospital, Ankara, Turkey.
  • Kutluk G; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Akdeniz University, Antalya, Turkey.
  • Topal E; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Ataturk University, Erzurum, Turkey.
  • Sayar E; Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Turkey.
  • Celikel C; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.
  • Houwen RHJ; Division of Allergy and Immunology, Department of Pediatrics, Ministry of Health, Marmara University, Istanbul, Turkey.
  • Bingol A; Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey.
  • Ogulur I; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Baskent University Hospital, Ankara, Turkey.
  • Eltan SB; Human Immunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.
  • Snow AL; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.
  • Lake C; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Kanuni Sultan Süleyman Training and Research Hospital, Health Sciences University, Istanbul, Turkey.
  • Fantoni G; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Inonu University, Malatya, Turkey.
  • Alba C; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Alanya Alaaddin Keykubat University, Alanya, Turkey.
  • Sellers B; Department of Pathology, School of Medicine, Marmara University, Istanbul, Turkey.
  • Chauvin SD; Department of Pediatric Gastroenterology, University Medical Center-Wilhelmina Children's Hospital, Utrecht, the Netherlands.
  • Dalgard CL; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Akdeniz University, Antalya, Turkey.
  • Harari O; Division of Allergy and Immunology, Department of Pediatrics, School of Medicine, Marmara University, Istanbul, Turkey.
  • Ni YG; Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Turkey.
  • Wang MD; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.
  • Devalaraja-Narashimha K; Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Turkey.
  • Subramanian P; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.
  • Ergelen R; Division of Allergy and Immunology, Department of Pediatrics, Ministry of Health, Marmara University, Istanbul, Turkey.
  • Artan R; Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Guner SN; Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Dalgic B; Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation, NIH, Bethesda, MD, USA.
  • Tsang J; The American Genome Center, Henry Jackson Foundation, Uniformed Services University of Health Sciences, Bethesda, MD, USA.
  • Belkaid Y; Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation, NIH, Bethesda, MD, USA.
  • Ertem D; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.
  • Baris S; Molecular Development of the Immune System Section and NIAID Clinical Genomics Program, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.
  • Lenardo MJ; Department of Anatomy, Physiology and Genetics, The American Genome Center, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Nat Immunol ; 22(2): 128-139, 2021 02.
Article in En | MEDLINE | ID: mdl-33398182
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Losing Enteropathies / Complement C5 / Complement Activation / Energy Metabolism / Complement Inactivating Agents / Antibodies, Monoclonal, Humanized / Hypoproteinemia / Immunity, Innate Type of study: Observational_studies Limits: Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: Turquía Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Losing Enteropathies / Complement C5 / Complement Activation / Energy Metabolism / Complement Inactivating Agents / Antibodies, Monoclonal, Humanized / Hypoproteinemia / Immunity, Innate Type of study: Observational_studies Limits: Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: Turquía Country of publication: Estados Unidos