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Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP.
Li, Zhigang; Moniruzzaman, Mohammed; Dastgheyb, Raha M; Yoo, Seung-Wan; Wang, Meina; Hao, Hongbo; Liu, Jia; Casaccia, Patrizia; Nogueras-Ortiz, Carlos; Kapogiannis, Dimitrios; Slusher, Barbara S; Haughey, Norman J.
Affiliation
  • Li Z; Department of Neurology, Richard T. Johnson Division of Neuroimmunology and Neurological Infections Johns Hopkins University School of Medicine Baltimore Maryland USA.
  • Moniruzzaman M; Department of Neurology, Richard T. Johnson Division of Neuroimmunology and Neurological Infections Johns Hopkins University School of Medicine Baltimore Maryland USA.
  • Dastgheyb RM; Department of Neurology, Richard T. Johnson Division of Neuroimmunology and Neurological Infections Johns Hopkins University School of Medicine Baltimore Maryland USA.
  • Yoo SW; Department of Neurology, Richard T. Johnson Division of Neuroimmunology and Neurological Infections Johns Hopkins University School of Medicine Baltimore Maryland USA.
  • Wang M; Department of Neurology, Richard T. Johnson Division of Neuroimmunology and Neurological Infections Johns Hopkins University School of Medicine Baltimore Maryland USA.
  • Hao H; Advanced Science Research Center at the Graduate Center, Neuroscience Initiative City University of New York New York New York USA.
  • Liu J; Advanced Science Research Center at the Graduate Center, Neuroscience Initiative City University of New York New York New York USA.
  • Casaccia P; Advanced Science Research Center at the Graduate Center, Neuroscience Initiative City University of New York New York New York USA.
  • Nogueras-Ortiz C; Laboratory of Clinical Investigation National Institute on Aging Baltimore Maryland USA.
  • Kapogiannis D; Laboratory of Clinical Investigation National Institute on Aging Baltimore Maryland USA.
  • Slusher BS; Department of Neurology, Richard T. Johnson Division of Neuroimmunology and Neurological Infections Johns Hopkins University School of Medicine Baltimore Maryland USA.
  • Haughey NJ; Johns Hopkins Drug Discovery Johns Hopkins University School of Medicine Baltimore Maryland USA.
J Extracell Vesicles ; 10(2): e12035, 2020 12.
Article in En | MEDLINE | ID: mdl-33408815
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytes / Amyloid beta-Protein Precursor / Casein Kinase I / Interleukin-1beta / Alzheimer Disease / Extracellular Vesicles / Inflammation / Neurons Type of study: Observational_studies / Prognostic_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Extracell Vesicles Year: 2020 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytes / Amyloid beta-Protein Precursor / Casein Kinase I / Interleukin-1beta / Alzheimer Disease / Extracellular Vesicles / Inflammation / Neurons Type of study: Observational_studies / Prognostic_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Extracell Vesicles Year: 2020 Document type: Article