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The 3-O-sulfation of heparan sulfate modulates protein binding and lyase degradation.
Chopra, Pradeep; Joshi, Apoorva; Wu, Jiandong; Lu, Weigang; Yadavalli, Tejabhiram; Wolfert, Margreet A; Shukla, Deepak; Zaia, Joseph; Boons, Geert-Jan.
Affiliation
  • Chopra P; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602.
  • Joshi A; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602.
  • Wu J; Department of Chemistry, University of Georgia, Athens, GA 30602.
  • Lu W; Department of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University of Medicine, Boston, MA 02118.
  • Yadavalli T; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602.
  • Wolfert MA; Department of Chemistry, University of Georgia, Athens, GA 30602.
  • Shukla D; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612.
  • Zaia J; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602.
  • Boons GJ; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CG Utrecht, The Netherlands.
Proc Natl Acad Sci U S A ; 118(3)2021 01 19.
Article in En | MEDLINE | ID: mdl-33441484

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfates / Sulfotransferases / Herpesvirus 1, Human / Heparin Lyase / Epithelial Cells / Heparitin Sulfate Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfates / Sulfotransferases / Herpesvirus 1, Human / Heparin Lyase / Epithelial Cells / Heparitin Sulfate Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Country of publication: Estados Unidos