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Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report.
Nourié, Nicole; Chamaa, Mohamed Ammar; Mouawad, Sarah; Kotait, Micheline Mia; Finianos, Serge; Azar, Hiba; Chelala, Dania.
Affiliation
  • Nourié N; Nephrology Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon. nicolenourie@yahoo.com.
  • Chamaa MA; Pulmonary and Critical Care Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon.
  • Mouawad S; Nephrology Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon.
  • Kotait MM; Nephrology Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon.
  • Finianos S; Nephrology Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon.
  • Azar H; Nephrology Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon.
  • Chelala D; Nephrology Department, Saint-Joseph University, Hôtel Dieu de France, Beirut, Lebanon.
CEN Case Rep ; 10(3): 364-369, 2021 08.
Article in En | MEDLINE | ID: mdl-33502716
ABSTRACT
Coronavirus disease 2019 (COVID-19) is a rapidly spreading infective disease caused by the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). The management of this disease remains a challenge particularly in certain subgroups of patients such in hemodialysis patients who have higher exposure rates due to the nature of their in-hospital care, and higher mortality due to their burden of comorbidities. We report a case of a 52-year-old patient with Von Hippel Lindau syndrome and end-stage renal disease on hemodialysis who contracted COVID-19 infection. Despite the patient's rapidly deteriorating clinical status he was successfully treated with Tocilizumab, after which he showed rapid improvement in his clinical, biological and radiological parameters. Although few studies were available regarding the use of Tocilizumab in the dialysis population, its use proved to be effective and well tolerated in our patient.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Renal Dialysis / Antibodies, Monoclonal, Humanized / COVID-19 Drug Treatment / Kidney Failure, Chronic Limits: Humans / Male / Middle aged Language: En Journal: CEN Case Rep Year: 2021 Document type: Article Affiliation country: Líbano

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Renal Dialysis / Antibodies, Monoclonal, Humanized / COVID-19 Drug Treatment / Kidney Failure, Chronic Limits: Humans / Male / Middle aged Language: En Journal: CEN Case Rep Year: 2021 Document type: Article Affiliation country: Líbano
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