Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development.

Marquez, Jorge; Dong, Jianping; Dong, Chun; Tian, Changsheng; Serrero, Ginette

Marquez, Jorge; Dong, Jianping; Dong, Chun; Tian, Changsheng; Serrero, Ginette.

Affiliation

Marquez J; Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America.
Dong J; Department of Pharmaceutical Sciences, University of Maryland, Baltimore School of Pharmacy, Baltimore, Maryland, United States of America.
Dong C; Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America.
Tian C; Precision Antibody Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America.
Serrero G; Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America.

PLoS One ; 16(1): e0246197, 2021.

Article in En | MEDLINE | ID: mdl-33503070

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Drug Development / Saporins / Neoplasm Proteins / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Estados Unidos

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