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Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Xiao, Peng; Yan, Wei; Gou, Lu; Zhong, Ya-Ni; Kong, Liangliang; Wu, Chao; Wen, Xin; Yuan, Yuan; Cao, Sheng; Qu, Changxiu; Yang, Xin; Yang, Chuan-Cheng; Xia, Anjie; Hu, Zhenquan; Zhang, Qianqian; He, Yong-Hao; Zhang, Dao-Lai; Zhang, Chao; Hou, Gui-Hua; Liu, Huanxiang; Zhu, Lizhe; Fu, Ping; Yang, Shengyong; Rosenbaum, Daniel M; Sun, Jin-Peng; Du, Yang; Zhang, Lei; Yu, Xiao; Shao, Zhenhua.
Affiliation
  • Xiao P; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biolog
  • Yan W; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Gou L; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.
  • Zhong YN; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Kong L; National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201204, China.
  • Wu C; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Wen X; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Yuan Y; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Cao S; School of Life and Health Sciences, Kobilka Institute of Innovative Drug Discovery, Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.
  • Qu C; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Yang X; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Yang CC; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Xia A; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Hu Z; Warshel Institute for Computational Biology, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.
  • Zhang Q; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
  • He YH; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; School of Pharmacy, Binzhou Medical University, Yantai, Shandon
  • Zhang DL; School of Pharmacy, Binzhou Medical University, Yantai, Shandong 264003, China.
  • Zhang C; Biomedical Isotope Research Center, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Hou GH; Biomedical Isotope Research Center, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
  • Liu H; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
  • Zhu L; Warshel Institute for Computational Biology, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.
  • Fu P; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Yang S; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Rosenbaum DM; Department of Biophysics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Sun JP; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Department of Physiology and Pathophysiology, School of Basic M
  • Du Y; School of Life and Health Sciences, Kobilka Institute of Innovative Drug Discovery, Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China. Electronic address: yangdu@cuhk.edu.cn.
  • Zhang L; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China. Electronic address: zhangleio@mail.xjtu.edu.cn.
  • Yu X; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China. Electronic address: yuxiao@sdu.edu.cn.
  • Shao Z; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China. Electronic address: zhenhuashao@scu.edu.cn.
Cell ; 184(4): 943-956.e18, 2021 02 18.
Article in En | MEDLINE | ID: mdl-33571432
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, Dopamine D1 / GTP-Binding Protein alpha Subunits, Gs Limits: Humans Language: En Journal: Cell Year: 2021 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, Dopamine D1 / GTP-Binding Protein alpha Subunits, Gs Limits: Humans Language: En Journal: Cell Year: 2021 Document type: Article Country of publication: Estados Unidos