Circulation of enterovirus A71 during 2019-2020, Marseille, France.
J Med Virol
; 93(8): 5163-5166, 2021 08.
Article
in En
| MEDLINE
| ID: mdl-33605462
ABSTRACT
Enteroviruses A71 (EVs-A71) are known to cause serious neurological infections, especially in the pediatric population. We report here eight cases of EV-A71 infection diagnosed in Marseille over the past 2 years (seven cases in 2019 and one case in 2020). Only children under 5 years of age were affected, including one case of acute flaccid paralysis. Viral RNA was detected by RT-PCR in peripheral samples for all cases (feces and upper respiratory samples). Phylogenetic analyses based on VP1 and 2C3C coding regions revealed that all these cases of EV-A71 infection were caused by viruses belonging to the subgenogroup C1 that currently circulates in Europe and that these viruses are genetically closed to other EVs-A71 recently detected in European countries. These data therefore reinforce the usefulness of the enterovirus surveillance network and the need for systematic screening for EV-A71 in case of an enteroviral infection. This study therefore suggests that the systematic screening for EV-A71 in case of enteroviral infection could provide additional data for enterovirus surveillance networks.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Enterovirus A, Human
/
Enterovirus Infections
Type of study:
Diagnostic_studies
/
Observational_studies
Limits:
Child, preschool
/
Humans
/
Infant
/
Newborn
Country/Region as subject:
Europa
Language:
En
Journal:
J Med Virol
Year:
2021
Document type:
Article
Affiliation country:
Francia
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA