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A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells.
Alvarez-Palomo, Ana Belén; Requena-Osete, Jordi; Delgado-Morales, Raul; Moreno-Manzano, Victoria; Grau-Bove, Carme; Tejera, Agueda M; Otero, Manel Juan; Barrot, Carme; Santos-Barriopedro, Irene; Vaquero, Alejandro; Mezquita-Pla, Jovita; Moran, Sebastian; Naya, Carlos Hobeich; Garcia-Martínez, Iris; Pérez, Francisco Vidal; Blasco, María A; Esteller, Manel; Edel, Michael J.
Affiliation
  • Alvarez-Palomo AB; Molecular Genetics and Control of Pluripotency Laboratory, Department of Biomedicine, Institute of Neuroscience, Faculty of Medicine, University of Barcelona, Hospital Clinic, Barcelona, Catalonia, Spain.
  • Requena-Osete J; Cell Therapy Service, Banc de Sang i Teixits (BST), Barcelona, Spain.
  • Delgado-Morales R; Molecular Genetics and Control of Pluripotency Laboratory, Department of Biomedicine, Institute of Neuroscience, Faculty of Medicine, University of Barcelona, Hospital Clinic, Barcelona, Catalonia, Spain.
  • Moreno-Manzano V; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Grau-Bove C; Division of Mental Health and Addiction, NORMENT, Centre for Mental Disorders Research, Oslo, Norway.
  • Tejera AM; Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Otero MJ; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, The Netherlands.
  • Barrot C; Neuronal and Tissue Regeneration Laboratory, Príncipe Felipe Research Center, Valencia, Spain.
  • Santos-Barriopedro I; Molecular Genetics and Control of Pluripotency Laboratory, Department of Biomedicine, Institute of Neuroscience, Faculty of Medicine, University of Barcelona, Hospital Clinic, Barcelona, Catalonia, Spain.
  • Vaquero A; Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
  • Mezquita-Pla J; Hospital Clinic, Department of Clinical Immunology, Biomedical Diagnostic Center (CDB), Villarroel, Catalonia, Spain.
  • Moran S; Forensic Genetics Laboratory, Legal Medicine Department, Faculty of Medicine, University of Barcelona, Barcelona, Spain.
  • Naya CH; Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Garcia-Martínez I; Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Pérez FV; Molecular Genetics and Control of Pluripotency Laboratory, Department of Biomedicine, Institute of Neuroscience, Faculty of Medicine, University of Barcelona, Hospital Clinic, Barcelona, Catalonia, Spain.
  • Blasco MA; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.
  • Esteller M; Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Edel MJ; Congenital Coagulopathies Department, Banc de Sang i Teixits (BST), Barcelona, Spain.
Stem Cells ; 39(7): 866-881, 2021 07.
Article in En | MEDLINE | ID: mdl-33621399
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Stem Cells Year: 2021 Document type: Article Affiliation country: España
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Stem Cells Year: 2021 Document type: Article Affiliation country: España