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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.
Yasuda, Tadahito; Koiwa, Mayu; Yonemura, Atsuko; Miyake, Keisuke; Kariya, Ryusho; Kubota, Sho; Yokomizo-Nakano, Takako; Yasuda-Yoshihara, Noriko; Uchihara, Tomoyuki; Itoyama, Rumi; Bu, Luke; Fu, Lingfeng; Arima, Kota; Izumi, Daisuke; Iwagami, Shiro; Eto, Kojiro; Iwatsuki, Masaaki; Baba, Yoshifumi; Yoshida, Naoya; Ohguchi, Hiroto; Okada, Seiji; Matsusaki, Keisuke; Sashida, Goro; Takahashi, Akiko; Tan, Patrick; Baba, Hideo; Ishimoto, Takatsugu.
Affiliation
  • Yasuda T; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Koiwa M; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Yonemura A; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Miyake K; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Kariya R; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
  • Kubota S; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Yokomizo-Nakano T; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Yasuda-Yoshihara N; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Uchihara T; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Itoyama R; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Bu L; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Fu L; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Arima K; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Izumi D; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Iwagami S; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Eto K; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Iwatsuki M; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Baba Y; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Yoshida N; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Ohguchi H; Division of Disease Epigenetics, Institute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan.
  • Okada S; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
  • Matsusaki K; Kanamecho Hospital, Tokyo, Japan.
  • Sashida G; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
  • Takahashi A; The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Tan P; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Baba H; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Center for Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. Electronic address: hdobaba@kumamoto-u.ac.jp.
  • Ishimoto T; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan. Electronic address: taka1516@kumamoto-u.ac.jp.
Cell Rep ; 34(8): 108779, 2021 02 23.
Article in En | MEDLINE | ID: mdl-33626356
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Neoplasms / Stomach Neoplasms / Cytokines / Inflammation Mediators / Cancer-Associated Fibroblasts / Senescence-Associated Secretory Phenotype Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cell Rep Year: 2021 Document type: Article Affiliation country: Japón
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Neoplasms / Stomach Neoplasms / Cytokines / Inflammation Mediators / Cancer-Associated Fibroblasts / Senescence-Associated Secretory Phenotype Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cell Rep Year: 2021 Document type: Article Affiliation country: Japón