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Glucosylceramide synthase inhibitors prevent replication of SARS-CoV-2 and influenza virus.
Vitner, Einat B; Achdout, Hagit; Avraham, Roy; Politi, Boaz; Cherry, Lilach; Tamir, Hadas; Yahalom-Ronen, Yfat; Paran, Nir; Melamed, Sharon; Erez, Noam; Israely, Tomer.
Affiliation
  • Vitner EB; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel. Electronic address: einatv@iibr.gov.il.
  • Achdout H; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Avraham R; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Politi B; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Cherry L; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Tamir H; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Yahalom-Ronen Y; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Paran N; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Melamed S; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Erez N; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
  • Israely T; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
J Biol Chem ; 296: 100470, 2021.
Article in En | MEDLINE | ID: mdl-33639165
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Pyrrolidines / Quinuclidines / Carbamates / Glycosphingolipids / Dioxanes / Influenza A Virus, H1N1 Subtype / SARS-CoV-2 / Glucosyltransferases Language: En Journal: J Biol Chem Year: 2021 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Pyrrolidines / Quinuclidines / Carbamates / Glycosphingolipids / Dioxanes / Influenza A Virus, H1N1 Subtype / SARS-CoV-2 / Glucosyltransferases Language: En Journal: J Biol Chem Year: 2021 Document type: Article Country of publication: Estados Unidos