GW117: A novel serotonin (5-HT2C ) receptor antagonist and melatonin (MT1 /MT2 ) receptor agonist with potential antidepressant-like activity in rodents.

Gao, Nana; Zheng, Wei; Murezati, Tiliwaerde; Gu, Wei; Li, Xiaorong; Jin, Zengliang

GW117: A novel serotonin (5-HT_2C ) receptor antagonist and melatonin (MT₁ /MT₂ ) receptor agonist with potential antidepressant-like activity in rodents.

Gao, Nana; Zheng, Wei; Murezati, Tiliwaerde; Gu, Wei; Li, Xiaorong; Jin, Zengliang.

Affiliation

Gao N; Department of Gastrointestinal Surgery and Clinical Nutrition, Beijing Shijitan Hospital,Captial Medical University, Beijing, China.
Zheng W; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Murezati T; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Gu W; Beijing Guangwei Pharmaceutical Technology Co., Ltd, Beijing, China.
Li X; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Jin Z; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.

CNS Neurosci Ther ; 27(6): 702-713, 2021 06.

Article in En | MEDLINE | ID: mdl-33650297

Subject(s)
Key words

5-HT2C receptor; GW117; antidepressant; melatonin receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Anxiety Agents / Receptor, Melatonin, MT1 / Receptor, Melatonin, MT2 / Serotonin 5-HT2 Receptor Antagonists / Antidepressive Agents Limits: Animals Language: En Journal: CNS Neurosci Ther Journal subject: NEUROLOGIA / TERAPEUTICA Year: 2021 Document type: Article Affiliation country: China

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