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Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
Langrish, Claire L; Bradshaw, J Michael; Francesco, Michelle R; Owens, Timothy D; Xing, Yan; Shu, Jin; LaStant, Jacob; Bisconte, Angelina; Outerbridge, Catherine; White, Stephen D; Hill, Ronald J; Brameld, Ken A; Goldstein, David M; Nunn, Philip A.
Affiliation
  • Langrish CL; Principia Biopharma Inc., South San Francisco, CA 94080; and claire.langrish@principiabio.com.
  • Bradshaw JM; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Francesco MR; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Owens TD; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Xing Y; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Shu J; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • LaStant J; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Bisconte A; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Outerbridge C; School of Veterinary Medicine, University of California Davis, Davis, CA 95616.
  • White SD; School of Veterinary Medicine, University of California Davis, Davis, CA 95616.
  • Hill RJ; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Brameld KA; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Goldstein DM; Principia Biopharma Inc., South San Francisco, CA 94080; and.
  • Nunn PA; Principia Biopharma Inc., South San Francisco, CA 94080; and.
J Immunol ; 206(7): 1454-1468, 2021 04 01.
Article in En | MEDLINE | ID: mdl-33674445
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basophils / Blood Platelets / Pemphigus / Purpura, Thrombocytopenic, Idiopathic / Protein Kinase Inhibitors / Agammaglobulinaemia Tyrosine Kinase / Kidney / Mast Cells / Anti-Inflammatory Agents / Nephritis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Immunol Year: 2021 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basophils / Blood Platelets / Pemphigus / Purpura, Thrombocytopenic, Idiopathic / Protein Kinase Inhibitors / Agammaglobulinaemia Tyrosine Kinase / Kidney / Mast Cells / Anti-Inflammatory Agents / Nephritis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Immunol Year: 2021 Document type: Article