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Population exposure-efficacy and exposure-safety analyses for rucaparib in patients with recurrent ovarian carcinoma from Study 10 and ARIEL2.
Konecny, Gottfried E; Oza, Amit M; Tinker, Anna V; Oaknin, Ana; Shapira-Frommer, Ronnie; Ray-Coquard, Isabelle; Aghajanian, Carol; Coleman, Robert L; O'Malley, David M; Leary, Alexandra; Chen, Lee-May; Provencher, Diane; Ma, Ling; Brenton, James D; Castro, Cesar; Green, Michelle; Simmons, Andrew D; Beltman, Jeri; Harding, Thomas; Lin, Kevin K; Goble, Sandra; Maloney, Lara; Kristeleit, Rebecca S; McNeish, Iain A; Swisher, Elizabeth M; Xiao, Jim J.
Affiliation
  • Konecny GE; Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA. Electronic address: GKonecny@mednet.ucla.edu.
  • Oza AM; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Tinker AV; Medical Oncology, BC Cancer Agency, Vancouver, BC, Canada.
  • Oaknin A; Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
  • Shapira-Frommer R; Department of Oncology, Chaim Sheba Medical Center, Tel HaShomer, Israel.
  • Ray-Coquard I; Medical Oncology Department, Centre Léon Bérard and University Claude Bernard and Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens (GINECO), Lyon, France.
  • Aghajanian C; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Coleman RL; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • O'Malley DM; Division of Gynecologic Oncology, The Ohio State University, James Cancer Center, Columbus, OH, USA.
  • Leary A; Gynecological Unit, Gustave Roussy Cancer Center, INSERM U981, GINECO, Villejuif, France.
  • Chen LM; Gynecologic Oncology Division, University of California San Francisco, San Francisco, CA, USA.
  • Provencher D; Institut du Cancer de Montréal, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montreal, QC, Canada.
  • Ma L; Medical Oncology, Rocky Mountain Cancer Centers, Lakewood, CO, USA.
  • Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Castro C; Cancer Center, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
  • Green M; Integrated Drug Development, Certara Strategic Consulting, Menlo Park, CA, USA.
  • Simmons AD; Molecular Diagnostics, Clovis Oncology, Inc., Boulder, CO, USA.
  • Beltman J; Regulatory Affairs, Clovis Oncology, Inc., Boulder, CO, USA.
  • Harding T; Molecular Diagnostics, Clovis Oncology, Inc., Boulder, CO, USA.
  • Lin KK; Molecular Diagnostics, Clovis Oncology, Inc., Boulder, CO, USA.
  • Goble S; Biostatistics, Clovis Oncology, Inc., Boulder, CO, USA.
  • Maloney L; Clinical Development, Clovis Oncology, Inc., Boulder, CO, USA.
  • Kristeleit RS; Department of Oncology, University College London (UCL) Cancer Institute, UCL Hospitals, London, UK.
  • McNeish IA; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Swisher EM; Division of Gynecologic Oncology, University of Washington, Seattle, WA, USA.
  • Xiao JJ; Clinical Pharmacology, Clovis Oncology, Inc., Boulder, CO, USA.
Gynecol Oncol ; 161(3): 668-675, 2021 06.
Article in En | MEDLINE | ID: mdl-33752918
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Carcinoma, Ovarian Epithelial / Indoles / Neoplasm Recurrence, Local Type of study: Prognostic_studies Limits: Aged / Female / Humans / Middle aged Language: En Journal: Gynecol Oncol Year: 2021 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Carcinoma, Ovarian Epithelial / Indoles / Neoplasm Recurrence, Local Type of study: Prognostic_studies Limits: Aged / Female / Humans / Middle aged Language: En Journal: Gynecol Oncol Year: 2021 Document type: Article Country of publication: Estados Unidos