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The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity.
Zhou, Jiajia; Kryczek, Ilona; Li, Shasha; Li, Xiong; Aguilar, Angelo; Wei, Shuang; Grove, Sara; Vatan, Linda; Yu, Jiali; Yan, Yijian; Liao, Peng; Lin, Heng; Li, Jing; Li, Gaopeng; Du, Wan; Wang, Weichao; Lang, Xueting; Wang, Weimin; Wang, Shaomeng; Zou, Weiping.
Affiliation
  • Zhou J; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Kryczek I; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Li S; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Li X; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Aguilar A; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Wei S; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Grove S; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Vatan L; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Yu J; Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Yan Y; Department of Pharmacology, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Liao P; Department of Medicinal Chemistry, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Lin H; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Li J; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Li G; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Du W; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Wang W; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Lang X; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Wang W; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Wang S; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Zou W; Department of Surgery, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Nat Immunol ; 22(4): 460-470, 2021 04.
Article in En | MEDLINE | ID: mdl-33767425
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes, Tumor-Infiltrating / CD8-Positive T-Lymphocytes / Proto-Oncogene Proteins c-mdm2 / STAT5 Transcription Factor / Neoplasms Limits: Animals / Female / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes, Tumor-Infiltrating / CD8-Positive T-Lymphocytes / Proto-Oncogene Proteins c-mdm2 / STAT5 Transcription Factor / Neoplasms Limits: Animals / Female / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos