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The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols.
Czekala, Lukasz; Chapman, Fiona; Simms, Liam; Rudd, Kathryn; Trelles Sticken, Edgar; Wieczorek, Roman; Bode, Lisa Maria; Pani, Jutta; Moelijker, Nynke; Derr, Remco; Brandsma, Inger; Hendriks, Giel; Stevenson, Matthew; Walele, Tanvir.
Affiliation
  • Czekala L; Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, UK.
  • Chapman F; Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, UK.
  • Simms L; Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, UK.
  • Rudd K; Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, UK.
  • Trelles Sticken E; Reemtsma Cigarettenfabriken GmbH, an Imperial Brands PLC Company, Albert-Einstein-Ring-7, D-22761 Hamburg, Germany.
  • Wieczorek R; Reemtsma Cigarettenfabriken GmbH, an Imperial Brands PLC Company, Albert-Einstein-Ring-7, D-22761 Hamburg, Germany.
  • Bode LM; Reemtsma Cigarettenfabriken GmbH, an Imperial Brands PLC Company, Albert-Einstein-Ring-7, D-22761 Hamburg, Germany.
  • Pani J; Reemtsma Cigarettenfabriken GmbH, an Imperial Brands PLC Company, Albert-Einstein-Ring-7, D-22761 Hamburg, Germany.
  • Moelijker N; Toxys B.V., Robert Boyleweg 4, 2333 CG Leiden, The Netherlands.
  • Derr R; Toxys B.V., Robert Boyleweg 4, 2333 CG Leiden, The Netherlands.
  • Brandsma I; Toxys B.V., Robert Boyleweg 4, 2333 CG Leiden, The Netherlands.
  • Hendriks G; Toxys B.V., Robert Boyleweg 4, 2333 CG Leiden, The Netherlands.
  • Stevenson M; Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, UK.
  • Walele T; Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, UK.
Mutagenesis ; 36(2): 129-142, 2021 05 31.
Article in En | MEDLINE | ID: mdl-33769537

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nicotiana / Propylene Glycol / Aneugens / Electronic Nicotine Delivery Systems / Glycerol / Mutagenicity Tests / Nicotine Type of study: Etiology_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mutagenesis Journal subject: GENETICA MEDICA / SAUDE AMBIENTAL Year: 2021 Document type: Article Affiliation country: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nicotiana / Propylene Glycol / Aneugens / Electronic Nicotine Delivery Systems / Glycerol / Mutagenicity Tests / Nicotine Type of study: Etiology_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mutagenesis Journal subject: GENETICA MEDICA / SAUDE AMBIENTAL Year: 2021 Document type: Article Affiliation country: Reino Unido